Article

Extracellular vesicular Wnt7b mediates HPV E6-induced cervical cancer angiogenesis by activating the β-catenin signaling pathway

2020-10-22

Abstract excerpt

<h4>Background: </h4> The E6 oncoproteins of human papillomavirus (HPV) 16/18 are the critical drivers of cervical cancer (CC) progression. Extracellular vesicles (EVs) are emerging as critical mediators of cancer-tumor microenvironment (TME) communication. However, whether EVs contribute to HPV 16/18 E6-mediated impacts on CC progression remains unclear. <h4>Methods: </h4>: A series of in vitro and in vivo assays...

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Literature Corpus work: 575d1ed5-801d-5529-99ce-6259e6f64f7f
DOI: 10.21203/rs.3.rs-27330/v2

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