Article

Nucleus Pulposus Cell Network Modelling in the Intervertebral Disc

2024-09-21

Abstract excerpt

Intervertebral disc degeneration (IDD) arises from an intricate imbalance between the anabolic and catabolic processes governing the extracellular matrix (ECM) within the disc. Biochemical processes are complex, redundant and feedback-looped, thus improved integration of knowledge is needed. To address this, a literature-based regulatory network model (RNM) for nucleus pulposus cells (NPC) is proposed, representin...

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Literature Corpus work: 56d7f69a-8326-5ba9-8e3b-be368a276cbb
DOI: 10.1101/2024.09.18.613636

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