Article

Sustained optogenetic expression in skeletal muscle is limited by host adaptive immunity, but preserved with targeted immunosuppression

2026-07-06

Abstract excerpt

<title>Abstract</title> <p>Obstructive sleep apnoea (OSA) is characterised by recurrent upper airway collapse during sleep due to inadequate neuromuscular compensation of the upper airway. Despite its high prevalence, affecting up to one billion people worldwide, existing therapies are often poorly tolerated or variably effective, leaving persistent residual disease and a major unmet clinical need. Optogenetic ap...

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Literature Corpus work: 5684d64d-5384-5e1a-b9bb-8667bbe62af6
DOI: 10.21203/rs.3.rs-10146411/v1

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Sustained optogenetic expression in skeletal muscle is limited by host adaptive immunity, but preserved with targeted immunosuppressionDOI 10.21203/rs.3.rs-10146411/v1Read

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