Article

MicroRNAs as potential therapeutics to enhance chemosensitivity in advanced prostate cancer

2018-02-28

Abstract excerpt

Docetaxel and cabazitaxel are taxane chemotherapy treatments for metastatic castration-resistant prostate cancer (CRPC). However, therapeutic resistance remains a major issue. MicroRNAs are short non-coding RNAs that can silence multiple genes, regulating several signalling pathways simultaneously. Therefore, synthetic microRNAs may have therapeutic potential in CRPC by regulating genes involved in taxane response...

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Literature Corpus work: 5626054c-8a59-58d1-95b5-82f6193fbe1a
DOI: 10.1101/273284

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