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Article

miR-130a activates apoptotic signaling through activation of caspase-8 in taxane-resistant prostate cancer cells

12 Jun 2015

Abstract excerpt

BACKGROUND: The acquisition of drug resistance is one of the most malignant phenotypes of cancer and identification of its therapeutic target is a prerequisite for the development of novel therapy. MicroRNAs (miRNAs) have been implicated in various types of cancer and proposed as potential therapeutic targets for patients. In the present study, we aimed to identify miRNA that could serve as a therapeutic target...

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PMID: 26074357
DOI: 10.1002/pros.23031

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