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Personalized reference genome-based pipeline reveals comprehensive haplotype-resolved views of cancer genomes

2026-05-30

Abstract excerpt

Cancer genome analysis relies on standard human reference genomes, but detecting somatic alterations in highly repetitive or individual-specific regions remains challenging. We developed the Personalized Reference genome-based Cancer Genome Analysis Pipeline (PRCGAP, https://github.com/yos-sk/PRCGAP), to our knowledge, the first comprehensive pipeline integrating haplotype-resolved analyses of somatic point mutati...

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Literature Corpus work
561e6e39-8a1e-5779-b09d-63e866bbd641
DOI
10.64898/2026.05.28.728591
Open publication

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Personalized reference genome-based pipeline reveals comprehensive haplotype-resolved views of cancer genomesDOI 10.64898/2026.05.28.728591
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