Article

Mapping pathogenic patterns in membrane transporters from the GLUT transporter family

2026-07-02

Abstract excerpt

Non-synonymous amino acid substitutions (missense mutations) are common in the general population; some are causative of serious disease. Depending on their structural context, they can disrupt protein function, folding, or dynamics. Computational predictive methods developed in recent years, such as AlphaMissense, provide new insights into how missense mutations affect protein structure by predicting and mapping...

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Literature Corpus work: 55930b1b-4e43-5f64-8904-99cb2a94206f
DOI: 10.64898/2026.06.28.735151

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