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Exposure to rotenone triggers redox driven system-wide lipidome alterations and metabolic trade-offs linked to Parkinson’s disease

2025-02-12

Abstract excerpt

With the global rise in aging populations, the increasing incidence of neurodegenerative diseases underscores concerns about brain health, with pesticides like rotenone, emerging as key environmental hazardous. The precise mechanism by which chronic environmental concentration of rotenone exposure causes Parkinson-like phenotype is not understood. Previous studies showed that rotenone induces depletion of dopamine...

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Literature Corpus work
5528abef-6025-5216-a4c1-4b537c4a2f9d
DOI
10.1101/2025.02.10.637453
Open publication

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Exposure to rotenone triggers redox driven system-wide lipidome alterations and metabolic trade-offs linked to Parkinson’s diseaseDOI 10.1101/2025.02.10.637453
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