Article

Heat-denaturation of conformational structures on nervous necrosis virus for generating neutralization antibodies

2018-02-01

Abstract excerpt

Nervous necrosis virus (NNV) belongs to genus Betanodavirus within family of Nodaviridae. It is highly pathogenic to various marine fishes. In this study, we determined conformational structures of NNV epitopes for generating NNV-neutralizing antibodies using several rabbit antisera and mouse monoclonal antibodies (MAbs). Rabbit antiserum against naïve NNV particles (anti-NNV serum) with high NNV-neutralization ac...

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Literature Corpus work: 54cdbf5d-6a90-59c6-a245-050d24128950
DOI: 10.1016/j.aquaculture.2017.10.034

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