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Sites responsible for infectivity and antigenicity on nervous necrosis virus (NNV) appear to be distinct

11 Feb 2021

Abstract excerpt

Abstract Nervous necrosis virus (NNV) is a pathogenic fish-virus belonging to the genus Betanodavirus ( Nodaviridae ). Surface protrusions on NNV particles play a crucial role in both antigenicity and infectivity. We exposed purified NNV particles to different physicochemical conditions to investigate the effects on antigenicity and infectivity, in order to reveal information regarding the conformational...

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PMID: 33574489
DOI: 10.1038/s41598-021-83078-3

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