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A systems‐level study reveals host‐targeted repurposable drugs against SARS‐CoV‐2 infection

1 Aug 2021

Abstract excerpt

Understanding the mechanism of SARS-CoV-2 infection and identifying potential therapeutics are global imperatives. Using a quantitative systems pharmacology approach, we identified a set of repurposable and investigational drugs as potential therapeutics against COVID-19. These were deduced from the gene expression signature of SARS-CoV-2-infected A549 cells screened against Connectivity Map and prioritized by...

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PMID: 34339582
DOI: 10.15252/msb.202110239

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