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Phylogenetic <em>In Silico</em> Analysis Indicates that the Moonlighting 14-3-3 Protein of <em>Ajellomycetaceae </em>Family and <em>Homo sapiens </em>Share Conserved and Distinct Features in Their Peptide Binding Site

2024-09-30

Abstract excerpt

The 14-3-3 protein in dimorphic fungi from the Ajellomycetaceae family, including Blastomyces spp., Histoplasma spp., Paracoccidioides spp., Emergomyces spp., and Emmonsia spp., play a crucial role in host-pathogen interactions. Thus, we performed a comparative genomic analysis across 21 fungal species which revealed the presence of two 14-3-3 gene copies in most fungi, with exceptions in Histoplasma ohiense and E...

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Literature Corpus work
547b0a5f-7020-53c0-b2c3-6542a290847a
DOI
10.20944/preprints202409.2323.v1
Open publication

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Phylogenetic <em>In Silico</em> Analysis Indicates that the Moonlighting 14-3-3 Protein of <em>Ajellomycetaceae </em>Family and <em>Homo sapiens </em>Share Conserved and Distinct Features in Their Peptide Binding SiteDOI 10.20944/preprints202409.2323.v1
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