Article

Experimental SARS-CoV-2 infection using horseshoe bats

2026-03-25

Abstract excerpt

Horseshoe bats are known as the natural reservoir of sarbecoviruses. To understand how horseshoe bats coexist with sarbecoviruses in nature, experimental infection can provide direct evidence. However, in vivo infection studies using horseshoe bats have been lacking because of the difficulty of maintaining insectivorous bats in a laboratory setting. Here, we established a stable husbandry system for greater horse...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 540be4b4-9a48-511d-bbdb-b891ef50b312
DOI: 10.64898/2026.03.19.712934

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Experimental SARS-CoV-2 infection using horseshoe batsDOI 10.64898/2026.03.19.712934Read

SARS-CoV-2 infection leads to acute infection with dynamic cellular and inflammatory flux in the lung that varies across nonhuman primate speciesSemantic proximity Read

Comparative analysis of single cell lung atlas of bat, cat, tiger and pangolinSemantic proximity Read

The post-acute phase of SARS-CoV-2 infection in two macaques species is associated with signs of ongoing virus replication and pathology in pulmonary and extrapulmonary tissuesSemantic proximity Read

Experimental and natural infections of severe acute respiratory syndrome-related coronavirus 2 in pets and wild and farm animalsSemantic proximity Read

Reconstructing bat antiviral immunity using epithelial organoidsSemantic proximity Read

Age-dependent pathogenic characteristics of SARS-CoV-2 infection in ferretsSemantic proximity Read

Single-cell transcriptional atlas of the Chinese horseshoe bat ( <i>Rhinolophus sinicus</i> ) provides insight into the cellular mechanisms which enable bats to be viral reservoirsSemantic proximity Read

Host gene expression profiles in ferrets infected with genetically distinct henipavirus strainsSemantic proximity Read

SARS-CoV-2 Utilization of ACE2 from Different Bat Species Allows for Virus Entry and Replication In VitroSemantic proximity Read

Animal Models of SARS-CoV-2: A Systematic ReviewSemantic proximity Read

Clinicopathologic features of a feline SARS-CoV-2 infection model parallel acute COVID-19 in humansSemantic proximity Read

Evaluation of alpaca tracheal explants as an ex vivo model for the study of Middle East respiratory syndrome coronavirus (MERS-CoV) infectionSemantic proximity Read