Article

Ubiquitin-specific protease-44 inhibits the proliferation and migration of cells via inhibition of JNK pathway in clear cell renal cell carcinoma

2020-03-04

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Clear cell renal cell carcinoma (ccRCC) is the most common form of adult kidney cancer. Ubiquitin-specific protease (USP)44 has been reported to be involved in various cancers. We investigated the function, role and molecular mechanism of USP44 in ccRCC. <bold>Methods:</bold> Data obtained from the Cancer Genome Atlas Data Portal and Gene Expression Omnibus data...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 53ff3764-6a8b-517e-bcb0-0ff8eba4a5ec
DOI: 10.21203/rs.2.16522/v7

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Ubiquitin-specific protease-44 inhibits the proliferation and migration of cells via inhibition of JNK pathway in clear cell renal cell carcinomaDOI 10.21203/rs.2.16522/v7Read

Ubiquitin specific peptidase 53 inhibits the occurrence and development of clear cell renal cell carcinoma through NF-κB pathway inactivationSemantic proximity Read

Expression, Prognostic and Immunological Roles of USP8 in kidney renal clear cell carcinoma: An Integrated AnalysisSemantic proximity Read

Comprehensive Analysis of the Expression and Prognosis for <i>PSMBs</i> in Clear Cell Renal Cell CarcinomaSemantic proximity Read

Ubiquitin specific peptidase 21 regulates interleukin-8 expression, stem-cell like property of human renal cell carcinomaSemantic proximity Read

BAP1 serves as a clear-cell renal cell carcinoma suppressor and is inversely regulated by miR-200c-3pSemantic proximity Read

MiR-182-5p Inhibits the Tumorigenesis of clear cell renal cell carcinoma by Repressing UBE2TSemantic proximity Read

Knockdown of MAPK14 inhibits the proliferation and migration of clear cell renal cell carcinoma by downregulating the expression of CDC25BSemantic proximity Read

The tumor promoter role and molecular mechanism of C8orf76/CALB2 axis in clear cell renal cell carcinomaSemantic proximity Read

UBE2C contributes to malignant phenotypes in clear cell renal cell carcinoma via cell cycle and apoptosis regulation.Semantic proximity Read

Ubiquitin-Specific Protease 1 Promotes Bladder Cancer Progression by Stabilizing C-mycSemantic proximity Read

USP14 promotes colorectal cancer progression by targeting JNK for stabilizationSemantic proximity Read

Bioinformatic Analysis Identifying PSMB 1/2/3/4/6/8/9/10 as Prognostic Indicators in Clear Cell Renal Cell CarcinomaSemantic proximity Read