Article

Decontamination of ambient RNA in single-cell RNA-seq with DecontX

2019-07-16

Abstract excerpt

<h4>ABSTRACT</h4> Droplet-based microfluidic devices have become widely used to perform single-cell RNA sequencing (scRNA-seq) and discover novel cellular heterogeneity in complex biological systems. However, ambient RNA present in the cell suspension can be incorporated into these droplets and aberrantly counted along with a cell’s native mRNA. This results in cross-contamination of transcripts between different...

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Literature Corpus work: 5353dd4c-d9fd-5ff3-85a8-c66dbbccb20b
DOI: 10.1101/704015

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