Article

Variation in synonymous nucleotide composition among genomes of sarbecoviruses and consequences for the origin of COVID-19

2021-08-26

Abstract excerpt

The subgenus Sarbecovirus includes two human viruses, SARS-CoV and SARS-CoV-2, respectively responsible for the SARS epidemic and COVID-19 pandemic, as well as many bat viruses and two pangolin viruses. Here, the synonymous nucleotide composition (SNC) of Sarbecovirus genomes was analysed by examining third codon-positions, dinucleotides, and degenerate codons. The results show evidence for the eigth following...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5346d17e-2a7c-5627-a600-af25a0f9a419
DOI: 10.1101/2021.08.26.457807

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Variation in synonymous nucleotide composition among genomes of sarbecoviruses and consequences for the origin of COVID-19DOI 10.1101/2021.08.26.457807Read

Evolutionary origins of the SARS-CoV-2 sarbecovirus lineage responsible for the COVID-19 pandemicSemantic proximity Read

Synonymous mutations and the molecular evolution of SARS-Cov-2 originsSemantic proximity Read

Synonymous mutations and the molecular evolution of SARS-CoV-2 originsSemantic proximity Read

The substitution spectra of coronavirus genomes.Semantic proximity Read

Evolutionary Signatures Governing the Codon Usage Bias in Coronaviruses and Their Implications for Viruses Infecting Various Bat Species.Semantic proximity Read

Comparative analysis of human coronaviruses focusing on nucleotide variability and synonymous codon usage patternsSemantic proximity Read

Codon usage pattern reveals SARS-CoV-2 as a monomorphic pathogen of hybrid origin with role of silent mutations in rapid evolutionary successSemantic proximity Read

Base Composition and Host Adaptation of the SARS-CoV-2: Insight From the Codon Usage PerspectiveSemantic proximity Read

Comparative Analysis of Human Coronaviruses Focusing on Nucleotide Variability and Synonymous Codon Usage PatternSemantic proximity Read

Natural selection plays a significant role in governing the codon usage bias in the novel SARS-CoV-2 variants of concern (VOC)Semantic proximity Read

Retracing Phylogenetic, Host and Geographic Origins of Coronaviruses with Coloured Genomic Bootstrap Barcodes: SARS-CoV and SARS-CoV-2 as Case StudiesSemantic proximity Read

From SARS and MERS CoVs to SARS‐CoV‐2: Moving toward more biased codon usage in viral structural and nonstructural genesSemantic proximity Read