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Dysregulation of Transcription Factors: A Key Culprit Behind Neurodegenerative Disorders

28 Nov 2018

Abstract excerpt

Neurodegenerative diseases (NDs) are considered heterogeneous disorders characterized by progressive pathological changes in neuronal systems. Transcription factors are protein molecules that are important in regulating the expression of genes. Although the clinical manifestations of NDs vary, the pathological processes appear similar with regard to neuroinflammation, oxidative stress, and proteostasis, to which,...

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PMID: 30484370
DOI: 10.1177/1073858418811787

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