Article

Impact of B.1.1.7 variant mutations on antibody recognition of linear SARS-CoV-2 epitopes

2021-01-08

Abstract excerpt

In 579 COVID patients’ samples collected between March and July of 2020, we examined the effects of non-synonymous mutations harbored by the circulating B.1.1.7 strain on linear antibody epitope signal for spike glycoprotein and nucleoprotein. At the antigen level, the mutations only substantially reduced signal in 0.5% of the population. Although some epitope mutations reduce measured signal in up to 6% of the po...

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Literature Corpus work: 52c97e54-bb71-5306-ad14-268ee4133424
DOI: 10.1101/2021.01.06.20248960

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