Article
Electromechanical window negativity in genotyped long-QT syndrome patients: relation to arrhythmia risk.
European heart journal - 14 Jan 2015
ter Bekke Rachel M A, Haugaa Kristina H, van den Wijngaard Arthur, Bos J Martijn, Ackerman Michael J, Edvardsen Thor, Volders Paul G A
Abstract excerpt
AIM: Prolonged and dispersed left-ventricular (LV) contraction is present in patients with long-QT syndrome (LQTS). Electrical and mechanical abnormalities appear most pronounced in symptomatic individuals. We focus on the 'electromechanical window' (EMW; duration of LV-mechanical systole minus QT interval) in patients with genotyped LQTS. Profound EMW negativity heralds torsades de pointes in animal models of...
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