Article

OM-85 reduces SARS-COV-2 viral RNA expression in nasopharyngeal cells from COVID-19 patients

2022-07-29

Abstract excerpt

OM-85 is a bacterial lysate from common respiratory tract pathogens, with an excellent safety profile, widely used to prevent recurrent respiratory tract infections. Several studies have been reporting the antiviral roles of OM-85. Here we demonstrated the effect of ex-vivo OM-85 exposure in nasopharyngeal cells collected from COVID-19 patients. OM-85 decreased the SARS-CoV-2 N1 gene expression and increased RIG-...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 52653f05-0b0a-5ac2-a601-ab734c5add13
DOI: 10.1101/2022.07.29.502045

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

OM-85 reduces SARS-COV-2 viral RNA expression in nasopharyngeal cells from COVID-19 patientsDOI 10.1101/2022.07.29.502045Read

The Potential Therapeutic Effect of RNA Interference and Natural Products on COVID-19: A Review of the Coronaviruses InfectionSemantic proximity Read

Combination therapy with oral antiviral and anti-inflammatory drugs improves the efficacy of delayed treatment in severe COVID-19Semantic proximity Read

An oral non-covalent non-peptidic inhibitor of SARS-CoV-2 Mpro ameliorates viral replication and pathogenesis in vivoSemantic proximity Read

Comparison of SARS-CoV-2 variants of concern in primary human nasal cultures demonstrates Delta as most cytopathic and Omicron as fastest replicatingSemantic proximity Read

Comparison of SARS-CoV-2 variants of concern in primary human nasal cultures demonstrates Delta as most cytopathic and Omicron as fastest replicatingSemantic proximity Read

Type I and Type III Interferons Restrict SARS-CoV-2 Infection of Human Airway Epithelial CulturesSemantic proximity Read

A Novel Viral Assembly Inhibitor Blocks SARS-CoV-2 Replication in Airway Epithelial CellsSemantic proximity Read

The Antiviral Mechanism of Action of Molnupiravir in Humans with COVID-19Semantic proximity Read

Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profilesSemantic proximity Read

Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapySemantic proximity Read

Relative infectivity of the SARS-CoV-2 Omicron variant in human alveolar cellsSemantic proximity Read

A new generation Mpro inhibitor with potent activity against SARS-CoV-2 Omicron variantsSemantic proximity Read