Article

Prostaglandin I2 suppresses the development of gut-brain axis disorder in irritable bowel syndrome in rats

2022-09-01

Abstract excerpt

<h4>Background: </h4> and Purpose We attempted to clarify a role of prostaglandin (PG) I2 and its specific receptor, IP in the pathogenesis of irritable bowel syndrome (IBS). Experimetal Approach Using a maternal separation (MS)-induced rat IBS model, the effect of IP agonist on the development of IBS phenotype such as visceral hypersentivity and depressive state. To further investigate the mechanisms of IP signal...

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Literature Corpus work: 51182eff-20bf-5f32-aca9-84a4de2f1666
DOI: 10.22541/au.166206422.29548188/v1

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