Article

Recognizing and Differentiating Area Postrema Syndrome Across NMOSD, MOGAD, and GFAP Astrocytopathy

2026-08-28

Abstract excerpt

Area postrema syndrome (APS), intractable nausea, vomiting, and/or hiccups persisting beyond 48 hours, is a recognized presenting feature of neuromyelitis optica spectrum disorder (NMOSD) and, less commonly, of MOGAD and GFAP astrocytopathy. APS is still frequently misattributed to primary gastrointestinal disease, delaying immunotherapy by weeks to months. For years its pathophysiology was inferred largely from l...

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Literature Corpus work: 50794200-f308-5373-ac43-1923e9339f15
DOI: 10.20944/preprints202608.2141.v1

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