Article

Multi-organ signaling mobilizes tumor-associated erythroid cells expressing immune checkpoint molecules

2020-08-03

Abstract excerpt

Hematopoietic-derived cells are integral components of the tumor microenvironment and serve as critical mediators of tumor-host interactions. Cells derived from myeloid and lymphoid lineages perform well-established functions linked to cancer development, progression and response to therapy. It is unclear whether erythroid cells exert such host cell functions in cancer, but emerging evidence points to this possibi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4f6438ed-a37b-5a0d-b743-6e7d82cdd434
DOI: 10.1101/2020.07.31.231001

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Multi-organ signaling mobilizes tumor-associated erythroid cells expressing immune checkpoint moleculesDOI 10.1101/2020.07.31.231001Read

Multiorgan Signaling Mobilizes Tumor-Associated Erythroid Cells Expressing Immune Checkpoint MoleculesSemantic proximity Read

DYRK3 dual-specificity kinase attenuates erythropoiesis during anemia.Semantic proximity Read

Molecular insights into stress erythropoiesisSemantic proximity Read

Molecular Insights into the Oxygen-Sensing Pathway and Erythropoietin Expression Regulation in ErythropoiesisSemantic proximity Read

A mouse model for an erythropoietin-deficiency anemia.Semantic proximity Read

In vitro culture of stress erythroid progenitors identifies distinct progenitor populations and analogous human progenitorsSemantic proximity Read

Erythroblastic Island Macrophages Shape Normal Erythropoiesis and Drive Associated Disorders in Erythroid Hematopoietic DiseasesSemantic proximity Read

Molecular Landscapes and Models of Acute ErythroleukemiaSemantic proximity Read

Developmentally-faithful and effective human erythropoiesis in immunodeficient and Kit mutant mice.Semantic proximity Read

Characterization, regulation, and targeting of erythroid progenitors in normal and disordered human erythropoiesis.Semantic proximity Read

Chronic Restraint Stress Upregulates Erythropoiesis through Glucocorticoid StimulationSemantic proximity Read

A mouse model of adult-onset anaemia due to erythropoietin deficiency.Semantic proximity Read