Multiorgan Signaling Mobilizes Tumor-Associated Erythroid Cells Expressing Immune Checkpoint Molecules

Abstract excerpt

Hematopoietic-derived cells are integral components of the tumor microenvironment and serve as critical mediators of tumor-host interactions. Host cells derived from myeloid and lymphoid lineages perform well-established functions linked to cancer development, progression, and response to therapy. It is unclear whether host erythroid cells also contribute to shaping the path that cancer can take, but emerging...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Erythrocyte Function and Pathophysiology
• Share to Erythropoietin and Anemia Treatment
• Share to PARP inhibition in cancer therapy