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Rapid Report: Retinal gene and pathway modulation by benzathine penicillin: A potential link to Extensive Macular Atrophy with Pseudodrusen (EMAP) and neurodegeneration

2025-09-17

Abstract excerpt

Extensive Macular Atrophy with Pseudodrusen (EMAP) is a rare and rapidly progressive retinal disease marked by central vision loss, chorioretinal atrophy, and pseudodrusen, primarily affecting middle-aged individuals. Recent studies have identified a statistically significant association between long-term use of benzathine penicillin (BP) and the onset of EMAP. However, the molecular mechanisms underlying this rel...

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Literature Corpus work: 4f48f54b-8494-5807-814c-0c08e5547089
DOI: 10.1101/2025.09.15.676285

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