Transcriptional landscape of psoriasis identifies the involvement of IL36 and IL36RN

Abstract excerpt

BACKGROUND: In present study we performed whole transcriptome analysis in plaque psoriasis patients and compared lesional skin with non-lesional skin and with the skin from healthy controls. We sequenced total RNA from 12 lesional (LP), 12 non-lesional (NLP) and from 12 normal (C) skin biopsies. RESULTS: Compared with previous gene expression profiling studies we had three groups under analysis - LP, NLP and C....

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