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Glomerular filtration rate, neurofilament light, and phospho-tau 181 in a community-based cohort: the Shanghai Aging Study

2023-06-26

Abstract excerpt

<h4>Background: </h4> The blood-based biomarkers are approaching the clinical practice of Alzheimer’s disease (AD). Chronic kidney disease (CKD) has a potential confounding effect on peripheral protein levels. It is essential to characterize the impact of renal function on AD markers. Methods Plasma phospho-tau181 (P-tau181), and neurofilament light (NfL) were assayed via the Simoa HD-X platform in 1189 dementia-...

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Literature Corpus work
4ea9b32c-c3a2-5b59-8bc7-5203522739ca
DOI
10.21203/rs.3.rs-3084801/v1
Open publication

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