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Blood-based biomarkers for Alzheimer’s disease: influence of kidney function

2025-11-23

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Blood biomarkers may aid Alzheimer’s disease (AD) diagnosis; however, their reliability can be affected by systemic conditions such as kidney dysfunction (KD). We evaluated the impact of KD on plasma levels of amyloid-β (Aβ42/Aβ40), phosphorylated tau (p-Tau181, p-Tau217), and neurofilament light chain (NfL), and developed correction strategies. <bold>Methods...

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Literature Corpus work
22b4e27e-2eee-59b0-8ce4-2b1232560683
DOI
10.21203/rs.3.rs-8007954/v1
Open publication

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