Article

Swine H1N1 influenza virus variants with enhanced polymerase activity and HA stability promote airborne transmission in ferrets

2021-09-22

Abstract excerpt

<h4>ABSTRACT</h4> Understanding how animal influenza A viruses (IAVs) acquire airborne transmissibility in humans and ferrets is needed to prepare for and respond to pandemics. Here, we investigated in ferrets the replication and transmission of swine H1N1 isolates P4 and G15, whose majority population had decreased polymerase activity and poor HA stability, respectively. For both isolates, a minor variant was se...

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Literature Corpus work: 4e8bef83-5502-5154-b105-93aee13ffbf7
DOI: 10.1101/2021.09.22.461336

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