Article

fastVEP: A High-Performance Variant Effect Predictor Implemented in Rust

2026-04-16

Abstract excerpt

Annotating genomic variants with their predicted functional consequences is a required step in genomics research and clinical diagnostics. The Ensembl Variant Effect Predictor (VEP) is the community standard for this task, but its Perl implementation struggles with the variant call sets that modern sequencing studies produce. Here we present fastVEP, a complete reimplementation of the VEP variant annotation engine...

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Literature Corpus work: 4e67b306-7f47-531f-8426-23fdf87d5dfa
DOI: 10.64898/2026.04.14.718452

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