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Renoprotective Effect of S14G-Humanin on Renal Ischemia/Reperfusion Injury by Activation of STAT3 and ERK 1/2 Signal Transduction Pathways in Rats

2026-03-12

Abstract excerpt

<title>Abstract</title> <p>Renal ischemia/reperfusion (I/R) injury leads to acute tubular necrosis and renal failure, triggering pathological mechanisms including inflammation, reactive oxygen species generation, apoptosis, and mitochondrial dysfunction. The mitochondrial peptide Humanin (HN), known to possess anti-apoptotic and anti-inflammatory properties, has been shown to counteract oxidative stress and resto...

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Literature Corpus work
4d8842b0-ab17-5cd1-bd1c-8816f379dbe9
DOI
10.21203/rs.3.rs-9040130/v1
Open publication

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Renoprotective Effect of S14G-Humanin on Renal Ischemia/Reperfusion Injury by Activation of STAT3 and ERK 1/2 Signal Transduction Pathways in RatsDOI 10.21203/rs.3.rs-9040130/v1
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