Article

Cigarette smoke induces colon cancer by regulating the gut microbiota and related metabolites

2026-02-11

Abstract excerpt

The causal relationship between smoking and colorectal cancer (CRC) remains unclear. In this study, a cigarette smoke–exposed mouse model demonstrated that smoking significantly increased CRC incidence by inducing gut microbiota dysbiosis and altering related metabolites. Smoke exposure reduced beneficial bacteria (e.g., Lactobacillus), increased harmful bacteria (e.g., Firmicutes and Clostridium), elevated metabo...

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Literature Corpus work: 4caa4822-e918-5c89-8005-63af99f440d7
DOI: 10.64898/2026.01.30.702732

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