Article

KODA: An Agentic Framework for KEGG Orthology-Driven Discovery of Antimicrobial Drug Targets in Gut Microbiome

2025-06-01

Abstract excerpt

The gut microbiome plays a crucial role in human health and disease, influencing diverse biological processes such as immune regulation and nutrient metabolism. However, the complexity of micro-bial interactions and their metabolic cross-feeding dynamics remains poorly understood. This study proposes KODA, an agentic framework that integrates large language models (LLMs) and knowledge graphs (KGs) to facilitate th...

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Literature Corpus work: 4ca4c5ab-4ef3-5c9c-a5db-0a74bfdab798
DOI: 10.1101/2025.05.27.656480

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