Leveraging epigenetic biomarker proxies for precision medicine

Abstract excerpt

<h4>Background: </h4> Clinical and molecular biomarkers are central to disease risk stratification, but their direct measurement remains fragmented across cohorts and analytical platforms, limiting scalability and reuse in population-scale studies. Results. We developed DNAm-based surrogates, termed epigenetic biomarker proxies (EBPs), in 4,418 participants from the Massachusetts General Brigham Aging Biobank Coho...

Topics

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• Access to Information
• Cause of Death
• Data Mining
• Databases, Factual
• Epigenetics and DNA Methylation
• Health Status
• Health Status Indicators
• Information Dissemination

Identifiers and source

Literature Corpus work

4c8471e3-2cf7-5471-abfc-630e0a5f072e

DOI

10.1101/2024.12.06.24318612