Article

Analysis of a paediatric cohort of dyslipidaemic patients using unsupervised learning methods provides insights into the biochemical phenotypes of familial hypercholesterolemia

2022-07-19

Abstract excerpt

<h4>ABSTRACT</h4> Familial hypercholesterolaemia (FH) is a highly prevalent silent disease with known genetic causes and poor prognosis if undiagnosed into adulthood. Characterised by high levels of total cholesterol and low-density lipoprotein cholesterol from birth, the majority of cases that fit the clinical criteria for FH do not present mutations in the disease associated genes and seem to result from polygen...

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Literature Corpus work: 4c42a749-deed-5277-bb9d-9deed6b08c85
DOI: 10.1101/2022.07.17.22277724

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