Article

Gut Microbiota-Derived Indole-3-Acetic Acid Induces PCOS by Disrupting Granulosa Cell Function under Metabolic Stress

2026-07-15

Abstract excerpt

<title>Abstract</title> <p> Background Polycystic ovary syndrome (PCOS) is a multifactorial reproductive and metabolic disorder, but the mechanisms linking metabolic stress to ovarian dysfunction remain incompletely understood. Gut microbiota-derived metabolites have emerged as important mediators of host metabolism; however, their contribution to PCOS pathogenesis, particularly within the ovarian microenvironm...

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Literature Corpus work: 4bd92360-46e8-58f3-bebd-1b80ef9daa21
DOI: 10.21203/rs.3.rs-9879889/v1

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