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Article

BMI-stratified phenotypes of polycystic ovary syndrome: advances in gut microbiota research and personalized management strategies.

Frontiers in endocrinology - 1 Jan 2026

Su Bisha, Cao Yining, Ma Lin, Huang Jian

Abstract excerpt

Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine-metabolic disorder affecting 11%-13% of women of reproductive age. Based on body mass index (BMI), patients can be phenotypically classified into obese and non-obese subgroups: the obese PCOS is characterized by insulin resistance, hyperandrogenemia, and metabolic syndrome, with more pronounced metabolic risks; non-obese PCOS primarily manifests as...

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Identifiers

PMID: 41727680
DOI: 10.3389/fendo.2026.1734041
PMCID: PMC12920190

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