Article
Rational Molecular Design of Two-Photon Activated Temoporfin: A Computational Study for Advanced Photodynamic Therapy
2025-05-03
Abstract excerpt
Photodynamic therapy (PDT) is a promising, non-invasive cancer treatment that relies on the activation of photosensitizers (PS) by suitable light to produce cytotoxic reactive oxygen species. However, the efficiency of PDT is often hindered by the limited penetration of visible light into tissues, requiring the use of infrared activable PS. Furthermore, PS are usually prone to aggregation and present solubility is...
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Identifiers and source
- Literature Corpus work
- 4b8a300f-7d72-593b-8d34-cd629076e666
- DOI
- 10.1101/2025.05.02.651861