Article
A comparative proteomic analysis of Vibrio cholerae O1 wild-type cells versus a phoB mutant showed that the PhoB/PhoR system is required for full growth and rpoS expression under inorganic phosphate abundance.
Journal of proteomics - 28 Jun 2013
Lery Letícia M S, Goulart Carolina L, Figueiredo Felipe R, Verdoorn Karine S, Einicker-Lamas Marcelo, Gomes Fabio M, Machado Ednildo A, Bisch Paulo M, von Kruger Wanda M A
Abstract excerpt
PhoB/PhoR is a two-component system originally described as involved in inorganic phosphate (Pi) transport and metabolism under Pi limitation. In order to disclose other roles of this system, a proteomic analysis of Vibrio cholerae 569BSR and its phoB/phoR mutant under high Pi levels was performed. Most of the proteins downregulated by the mutant have roles in energy production and conversion and in amino acid...
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