Article
Endo-β-N-acetylglucosaminidase EndoE from infant gut Enterococcus faecalis neutralizes SARS-CoV-2 by interacting with the viral spike protein
2024-08-28
Abstract excerpt
<title>Abstract</title> <p>Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is extensively <italic>N</italic>-glycosylated, and unlike the receptor-binding domain of the S1 subunit which undergoes frequent mutations, the glycosylation sites remain conserved across most variants of concern. In this study, we cloned and purified EndoE, an endo-β-<italic>N</italic>-acetylglucosaminidase enzyme from an <i...
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Identifiers and source
- Literature Corpus work
- 4b61a5cb-00ad-51ae-bfd4-a01b5decb66b
- DOI
- 10.21203/rs.3.rs-4807732/v1
