Back to search

Article

Toxicity impacts on human adipose MSCs acutely exposed to Aroclor and non-Aroclor mixtures of PCBs

2022-11-17

Abstract excerpt

<h4>ABSTRACT</h4> PCBs accumulate in adipose where they may impact the growth and function of cells within the tissue. This is particularly concerning during adolescence when adipocytes expand rapidly. Herein we sought to understand how exposure to PCB mixtures found in U.S. schools affects human adipose mesenchymal stem/stromal cell (MSC) health and function. We investigated how exposure to Aroclor 1016 and Aroc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4b609322-dc47-5a39-904d-05b56bb9d649
DOI
10.1101/2022.11.17.516943
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Toxicity impacts on human adipose MSCs acutely exposed to Aroclor and non-Aroclor mixtures of PCBsDOI 10.1101/2022.11.17.516943
A mixture of endocrine disrupting chemicals linked to lower birth weight induces adipogenesis and transcriptional changes related to birth weight alterations and diabetesSemantic proximity
Human Preadipocytes Differentiated under Hypoxia following PCB126 Exposure during Proliferation: Effects on Differentiation, Glucose Uptake and Adipokine ProfileSemantic proximity
Effects of the Endocrine-Disrupting Chemical DDT on Self-Renewal and Differentiation of Human Mesenchymal Stem CellsSemantic proximity
Inflammatory Pathway Genes Belong to Major Targets of Persistent Organic Pollutants in Adipose CellsSemantic proximity
Systemic safety and immunophenotypic profiles of human adipose-derived mesenchymal stem cell exosomes: A comprehensive toxicological assessmentSemantic proximity
Maternal polystyrene nanoplastics exposure during pregnancy induces obesity development in adult offspring through disrupting lipid homeostasisSemantic proximity
Effects of mixed exposure to PFAS on adolescent non-alcoholic fatty liver disease: Integrating evidence from human cohorts, toxicogenomics, and animal models to uncover mechanisms and potential target sitesSemantic proximity
Endocrine-Mediated Mechanisms of Metabolic Disruption and New Approaches to Examine the Public Health ThreatSemantic proximity
Low-Dose Pesticide Mixture Induces Senescence in Normal Mesenchymal Stem Cells (MSC) and Promotes Tumorigenic Phenotype in Premalignant MSC.Semantic proximity
Mesenchymal Stromal Cells showed an alteration of differentiation potential under Environmental Micro and Nanoplastics ExposureSemantic proximity
Structurally-diverse, PPARγ-activating environmental toxicants induce adipogenesis and suppress osteogenesis in bone marrow mesenchymal stromal cells.Semantic proximity
Potentiation of Adipogenesis by Reactive Oxygen Species is a Unifying Mechanism in the Pro-adipogenic Properties of Bisphenol A and its New Structural AnaloguesSemantic proximity
Select a neighboring publication to make it the new centre.