Article
RNA-seq Identifies FOS as a Potential Therapeutic Target Activating Neural Stem Cells via miR-21/SOX2 Pathway in Hypertensive Intracerebral Hemorrhage
2026-07-07
Abstract excerpt
<title>Abstract</title> <p> Objective Intracerebral hemorrhage (ICH) is a severely devastating neurological disorder. At present, there is no specific effective therapy for ICH, and its pathophysiological mechanism remains incompletely elucidated. Herein, we attempted to identify blood mRNA biomarkers, potential therapeutic targets and pathways associated with ICH via RNA sequencing. Results Biological analysi...
Topics
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- Cancer-related gene regulation
- Ferroptosis and cancer prognosis
- Intracerebral and Subarachnoid Hemorrhage Research
- Intracranial Aneurysms: Treatment and Complications
- Kruppel-like factors research
- Neuroinflammation and Neurodegeneration Mechanisms
- Single-cell and spatial transcriptomics
- Vascular Malformations Diagnosis and Treatment
Identifiers and source
- Literature Corpus work
- 4b3661f8-89eb-5bdc-a2a4-d92bca871fa7
- DOI
- 10.21203/rs.3.rs-9806137/v1
