Article

Functionally redundant control of cardiac hypertrophic signaling by inositol 1,4,5-trisphosphate receptors

2016-09-13

Abstract excerpt

Calcium plays an integral role to many cellular processes including contraction, energy metabolism, gene expression, and cell death. The inositol 1,4,5-trisphosphate receptor (IP 3 R) is a calcium channel expressed in cardiac tissue. There are three IP 3 R isoforms encoded by separate genes. In the heart, the IP 3 R-2 isoform is reported to being most predominant with regards to expression levels and functional...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4afb62f4-26cb-5b6e-977f-481762c4d92d
DOI: 10.1101/075044

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Functionally redundant control of cardiac hypertrophic signaling by inositol 1,4,5-trisphosphate receptorsDOI 10.1101/075044Read

The IP3 receptor regulates cardiac hypertrophy in response to select stimuli.Semantic proximity Read

The phosphatidylinositol(4,5)bisphosphate-binding sequence of transient receptor potential channel canonical 4α is critical for its contribution to cardiomyocyte hypertrophy.Semantic proximity Read

Signaling pathways for cardiac hypertrophy and failure.Semantic proximity Read

Signaling mechanisms in thyroid hormone-induced cardiac hypertrophy.Semantic proximity Read

Inositol 1,4,5-trisphosphate-mediated sarcoplasmic reticulum-mitochondrial crosstalk influences adenosine triphosphate production via mitochondrial Ca2+ uptake through the mitochondrial ryanodine receptor in cardiac myocytes.Semantic proximity Read

Regulation of cardiac hypertrophy by intracellular signalling pathways.Semantic proximity Read

Calcium cycling proteins in heart failure, cardiomyopathy and arrhythmias.Semantic proximity Read

Signaling Pathways in Cardiac Myocyte HypertrophySemantic proximity Read

Subcellular compartmentalization of proximal Gαq-receptor signaling produces unique hypertrophic phenotypes in adult cardiac myocytes.Semantic proximity Read

Interferon regulatory factor 3 is a negative regulator of pathological cardiac hypertrophySemantic proximity Read

Molecular targets and regulators of cardiac hypertrophy.Semantic proximity Read

Cooperative Binding of ETS2 and NFAT Links Erk1/2 and Calcineurin Signaling in the Pathogenesis of Cardiac HypertrophySemantic proximity Read