Back to search

Article

1- and 2-Photon Phototherapeutic Effects of Ru(II) Polypyridine Complexes in the Hypoxic Centre of Large Multicellular Tumour Spheroids and Tumour-Bearing Mice

2020-06-08

Abstract excerpt

During the last decades, photodynamic therapy (PDT), an approved medical technique, has received increasing attention to treat certain types of cancer. Despite recent improvements, the treatment of large tumors remains a major clinical challenge due to the low ability of the photosensitizer (PS) to penetrate a 3D cellular architecture and the low oxygen concentrations present in the tumour centre. To mimic the c...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4af2bd93-3ade-5d9e-93cb-9865888c9db3
DOI
10.26434/chemrxiv.12440012.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
1- and 2-Photon Phototherapeutic Effects of Ru(II) Polypyridine Complexes in the Hypoxic Centre of Large Multicellular Tumour Spheroids and Tumour-Bearing MiceDOI 10.26434/chemrxiv.12440012.v1
Ruthenium Complexes for 1- and 2-Photon Photodynamic Therapy: From In Silico Prediction to In Vivo ApplicationsSemantic proximity
Polymeric Encapsulation of a Ruthenium Polypyridine Complex for Tumor Targeted 1- and 2-Photon Photodynamic TherapySemantic proximity
Mitochondria-Targeted Nanoplatforms For Enhanced Photodynamic Therapy Against Hypoxia TumorSemantic proximity
Photodynamic Therapy and Tumor Microenvironment-Targeting Strategies: A Novel Synergy at the Frontier of Cancer TreatmentSemantic proximity
Self-Assembly of Erlotinib-Platinum(II) Complexes for Epidermal Growth Factor Receptor-Targeted Photodynamic Therapy.Semantic proximity
Engineered MoS₂ Nanoplatforms for Drug-Enhanced Cancer Phototherapy: From Design Strategies to Translational OpportunitiesSemantic proximity
Bis[Pyrrolyl Ru(II)] Triads: a New Class of Photosensitizers for Metal-Organic Photodynamic TherapySemantic proximity
High-performance pyrite nano-catalyst driven photothermal/chemodynamic synergistic therapy for OsteosarcomaSemantic proximity
Natural Product-Based Photosensitizers for Photodynamic Therapy: Translational Potential and Pharmaceutical Strategies for Clinical TranslationSemantic proximity
A highly effective self-supplying photosensitizer drug for deep-tissue metastatic tumours treatmentSemantic proximity
Biodegradable Mesoporous Manganese Carbonate Nanocomposites for LED Light-Driven Cancer Therapy via Enhancing Photodynamic Therapy and Attenuating Survivin ExpressionSemantic proximity
Third row transition metals for the treatment of cancerSemantic proximity
Select a neighboring publication to make it the new centre.