Back to search

Article

Mechanism of N-Myc Downstream Regulated Gene-1 regulating Integrin expression to inhibit gastric cancer metastasis

2024-10-30

Abstract excerpt

<h4>Background</h4> N-myc downstream regulated gene-1 (NDRG1), the first member of the NDRG family, is widely distributed in various tissues and organs. In gastric cancer, the hypo-expression of NDRG1 has been positively associated with malignant biological behavior and poor prognosis. In-depth investigation of the potential regulatory mechanism of NDRG1 on gastric cancer is crucial for understanding the pathogen...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4ad26140-600e-52bd-87ac-ceb1b23d37ba
DOI
10.1101/2024.10.23.619963
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Mechanism of N-Myc Downstream Regulated Gene-1 regulating Integrin expression to inhibit gastric cancer metastasisDOI 10.1101/2024.10.23.619963
N-myc Downstream Regulated Gene 1 (NDRG1) Promotes Metastasis of Human Scirrhous Gastric Cancer Cells through Epithelial Mesenchymal TransitionSemantic proximity
NDRG1 expression is related to the progression and prognosis of gastric cancer patients through modulating proliferation, invasion and cell cycle of gastric cancer cellsSemantic proximity
The Function of N-Myc Downstream-Regulated Gene 2 (NDRG2) as a Negative Regulator in Tumor Cell MetastasisSemantic proximity
Prognostic value and immunological role of NDRG1 gene in pan-cancerSemantic proximity
Multifaceted and Intricate Oncogenic Mechanisms of NDRG1 in Head and Neck Cancer Depend on Its C-Terminal 3R-MotifSemantic proximity
ncRNAs-mediated high expression of ITGB1 correlates with poor prognosis and tumor immune infiltration in gastric cancerSemantic proximity
N-myc downstream-regulated gene 1 inhibits the proliferation of colorectal cancer through emulative antagonizing NEDD4-mediated ubiquitylation of p21Semantic proximity
CRISPR/Cas9-mediated Deletion of ITGB1 Decrerased the Proliferation, Survival and Motility of Gastric Cancer CellsSemantic proximity
NDRGs in Breast Cancer: A Review and In Silico AnalysisSemantic proximity
Silencing of Discoidin Domain Receptor-1 (DDR1) Concurrently Inhibits Multiple Steps of Metastasis Cascade in Gastric CancerSemantic proximity
NDRG1 in Cancer: A Suppressor, Promoter, or Both?Semantic proximity
Overexpression of FNDC1 Relates to Poor Prognosis and Its Knockdown Impairs Cell Invasion and Migration in Gastric CancerSemantic proximity
Select a neighboring publication to make it the new centre.