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Development of an in vitro model for animal species susceptibility to SARS-CoV-2 replication based on expression of ACE2 and TMPRSS2 in avian cells

2021-08-19

Abstract excerpt

<h4>ABSTRACT</h4> The SARS-CoV-2 (SC2) virus has caused a worldwide pandemic because of the virus’s ability to transmit efficiently human-to-human. A key determinant of infection is the attachment of the viral spike protein to the host receptor angiotensin-converting enzyme 2 (ACE2). Because of the presumed zoonotic origin of SC2, there is no practical way to assess every species susceptibility to SC2 by direct c...

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Literature Corpus work
4a5214dd-c223-56d4-aeef-e005476b8009
DOI
10.1101/2021.08.18.456916
Open publication

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Development of an in vitro model for animal species susceptibility to SARS-CoV-2 replication based on expression of ACE2 and TMPRSS2 in avian cellsDOI 10.1101/2021.08.18.456916
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