Article

Immuno-moodulin is Differentially Expressed in T Cells and Plasma in Obsessive-Compulsive Disorder Patients

2024-12-20

Abstract excerpt

Immuno-moodulin (Imood), a recently discovered protein expressed in T cells, is associated with anxiety-like behavior in mice. However, its mechanism of action in modulating neuroimmune interactions remains unclear. To investigate this problem, we characterized Imood in human blood and immune cells using neutralizing monoclonal antibodies, revealing its nature as an intrinsically disordered protein (IDP) with uniq...

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Literature Corpus work: 49959ede-22d5-50e2-937d-64eb4824c967
DOI: 10.1101/2024.12.16.628685

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