Article

Variants in <i>DNAJC13</i> Are Not Associated with Parkinson’s Disease Across Different Ancestral Backgrounds

2025-12-31

Abstract excerpt

<h4>Background</h4> DNAJC13 was initially linked to autosomal dominant (AD) Parkinson’s disease (PD) in a European Mennonite family carrying the p.N855S variant. However, imperfect segregation and conflicting reports of pathogenicity raised uncertainty of DNAJC13 ’s role in the disease. <h4>Objectives</h4> Explore the association between common and rare variants in DNAJC13 and Parkinson’s disease. <h4>Method...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 49476681-d048-5adb-9572-6385a356dcd2
DOI: 10.64898/2025.12.30.25343211

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Variants in <i>DNAJC13</i> Are Not Associated with Parkinson’s Disease Across Different Ancestral BackgroundsDOI 10.64898/2025.12.30.25343211Read

The genetic associations of DNAJC family members with Parkinson's disease: comprehensive evidence from burden analysis and Mendelian randomization.Semantic proximity Read

DNAJC13 genetic variants in parkinsonism.Semantic proximity Read

DNAJC13 mutation screening in patients with Parkinson's disease from South Italy.Semantic proximity Read

Analysis of DNAJC13 mutations in French-Canadian/French cohort of Parkinson's disease.Semantic proximity Read

Association study of <i>DNAJC13, UCHL1, HTRA2, GIGYF2</i> and <i>EIF4G1</i> with Parkinson’s diseaseSemantic proximity Read

DNAJC13 p.Asn855Ser mutation screening in Parkinson's disease and pathologically confirmed Lewy body disease patients.Semantic proximity Read

Multi-ancestry analysis of <i>POLG</i> variants in Parkinson’s diseaseSemantic proximity Read

DNAJ mutations are rare in Chinese Parkinson's disease patients and controls.Semantic proximity Read

DNAJC6 mutations are not common causes of early onset Parkinson's disease in Chinese Han population.Semantic proximity Read

Estimated genetics prevalence of early-onset Parkinson’s disease caused by<i>PRKN</i>mutationsSemantic proximity Read

Clinical Variability of SYNJ1-Associated Early-Onset ParkinsonismSemantic proximity Read

Clinical, positron emission tomography, and pathological studies of DNAJC13 p.N855S Parkinsonism.Semantic proximity Read