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Article

The genetic associations of DNAJC family members with Parkinson's disease: comprehensive evidence from burden analysis and Mendelian randomization.

Human genetics - 9 Apr 2026

Yang Dehao, Xu Jingxuan, Zhu Yusheng, Lu Yangguang, Yao Ruotong, Ye Zihan, Yu Bohuai, Chen Jiaxuan, Zhang Tingxuan, Liu Bowen, Huang Suwen, Chen Guangyong

Abstract excerpt

BACKGROUND: Recent studies suggested that genetic mutations in the DNAJC family might elevate the risk of Parkinson's disease (PD). Nevertheless, the role of some DNAJC genes in PD remains controversial, and previous studies lacked downstream research. In this study, we aim to explore the relationship between DNAJC family genes and PD in a European cohort through a comprehensive method. METHODS: Rare variants...

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Source

Identifiers

PMID: 41951985
DOI: 10.1007/s00439-026-02831-8

Genes

DNAJC13
DNAJC1
DNAJC10
DNAJC11
DNAJC16
DNAJC27
DNAJC6
DNAJC19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

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The genetic associations of DNAJC family members with Parkinson's disease: comprehensive evidence from burden analysis and Mendelian randomization.PMID 41951985Read ↗

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