Article

Comprehensive analysis of the miRNA-mRNA pathological regulatory network of intestinal CD4+ T cells in Parkinson's disease

2023-03-27

Abstract excerpt

Infiltration of CD4+ T cells was found in brain tissue samples from PD patients, suggesting their involvement in developing central nervous system (CNS) disease. The idea of the gut-brain axis further corroborates intestinal T cells' activation as the central immune response initiation. However, the specific factors and molecular pathways regulating intestinal T-cell activation are unclear. We used the GSE156287 a...

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Literature Corpus work: 49205202-75b1-5740-8109-2c4e99bfd46b
DOI: 10.21203/rs.3.rs-2717723/v1

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